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What is Plasma donation and what is it for ?

A simple explanation about plasma therapy for commoners

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What is plasma

Our blood has plasma and blood cells. Plasma is liquid, blood cells are red blood cells, white blood cells (that produces antibodies) and platelets. Plasma is the liquid that has essential protein. The protein is extracted, collected and adjusted and used to treat people with immune deficiency disorder of same kind.

How does it work?

Antibodies developed against disease if completely recovered can be found in plasma, so it’s donated to any other person with same blood group affected with same disease to strengthen immune system and defeat the disease.

To put it in a perspective, blood donated by people who’ve recovered from COVID-19 has antibodies to the virus that causes it. The donated blood is processed to remove blood cells, leaving behind liquid (plasma) and antibodies. These can be given to people with COVID-19 with same blood group to boost their ability to fight the virus.

NOTE: Donating plasma is a bit more complicated than donating Blood, takes longer, blood is drawn out and cycled back to your body while plasma is extracted from it. Takes about 45 minutes to an hour unlike few minutes in case of blood donation.

In another words

When you are infected with any disease, your body produces antibodies to fight with the disease. So it is known that whenever you recover from a disease completely, your body will have developed some kind of antibodies from the experience that your immune system got attacked last time, so this time we know what it is so, even if it enters the body, we are already equipped to fight it. So in Covid-19 case, the recovered patients might have developed some kind of specific antibodies to stop the attack. So plasma donation is the process where the blood of a person who has already recover from lets say covid-19 is given to the current sick covid-19 patients in the hope that recovered person’s antibodies might help in the recovery of the sick person. Also, vaccines works on the same process. Our vaccines contains some type of similar virus like covid-19 which if injected should be harmless. But in the process, the body recognizes such type of new virus so it alerts the body to produce new antibodies that are capable of fighting them the next time. So when we are infected with covid-19 virus, the antibody kicks in because it’s similar to the last infection therefore stopping it before hand. So after vaccination, we are immune to that disease. Although, it isn’t sure that plasma donation in the case of covid-19 works. But still, it might.

The above answers are gathered from a KMAG Page on same title. We only have compiled them together to form this article.

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Knowledge & Infos

Explained: Murder of John Lennon

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On the evening of 8 December 1980, English musician John Lennon, was fatally shot in the archway of the Dakota, his residence in New York City by a 25-year-old Beatles fan, Mark David Champan, who had travelled from Hawaii to shot John Lennon. Chapman planned the killing over the course of several months and waited for Lennon at the Dakota on the morning of 8 December.

Reason

Chapman stated that he was angered by Lennon’s lifestyle and public statements, especially his much-publicized remark about the Beatles being “more popular than Jesus” and the lyrics of his later songs “God” and “Imagine”. Chapman also said he was inspired by the fictional character Holden Caulfield from J. D. Salinger’s 1951 novel The Catcher in the Rye.

I would listen to this music and I would get angry at him, for saying [in the song “God”] that he didn’t believe in God, that he just believed in him and Yoko, and that he didn’t believe in the Beatles. This was another thing that angered me, even though this record had been done at least ten years previously. I just wanted to scream out loud, “Who does he think he is, saying these things about God and heaven and the Beatles?” Saying that he doesn’t believe in Jesus and things like that. At that point, my mind was going through a total blackness of anger and rage. So I brought the Lennon book home, into this The Catcher in the Rye milieu where my mindset is Holden Caulfield and anti-phoniness.

According to Chapman’s wife ,Gloria, “He was angry that Lennon would preach love and peace but yet have millions”. Chapman later said: “He told us to imagine no possessions and there he was, with millions of dollars and yachts and farms and country estates, laughing at people like me who had believed the lies and bought the records and built a big part of their lives around his music.” He also recalled having listened to Lennon’s solo albums in the weeks before the murder.

Chapman now, however, states that, he was young then and was foolish and selfish and was seeking self glory by killing the famous man.

Murder Scene Explained

Chapman planned the killing over the course of several months and waited for Lennon at the Dakota on the morning of 8 December. During the evening, he met Lennon, who signed his copy of the album Double Fantasy. Lennon left with his wife, Yoko Ono, for a recording session at Record Plant Studio. Later that night, Lennon and Ono returned to the Dakota. As Lennon and Ono walked towards the archway entrance of the building, Chapman fired five hollow-point bullets from a .38 special revolver, four of which hit Lennon in the back. Chapman then removed his coat and hat in preparation for the arrival of police—to show he was not carrying any concealed weapons—and remained standing on West 72nd Street. Underneath his coat, he wore a promotional T-shirt for the musician Todd Rundgren’s album Hermit of Mink Hollow. Perdomo shouted at Chapman, “Do you know what you’ve done?”, to which Chapman calmly replied, “Yes, I just shot John Lennon.” Chapman remained at the scene reading “The Catcher in the Rye” until he was arrested by the police.

Lennon was rushed in a police cruiser to Roosevelt Hospital, where he was pronounced dead on arrival.

The West 72nd Street entrance to the Dakota, where Lennon was shot

About Mark David Chapman

Mark David Chapman was born on May 10, 1955, in Fort Worth, Texas. By the time he was 14, Chapman was using drugs and skipping classes. He once ran away from home to live on the streets of Atlanta for two weeks. He said he was bullied at school because he was not a good athlete.

Mark David Chapman, now a 65-year-old man, is an American criminal who murdered John Lennon. More than a dozen psychologists and psychiatrists interviewed Chapman in the six months prior to his trial—three for the prosecution, six for the defense, and several more on behalf of the court—and they conducted a battery of standard diagnostic procedures and more than 200 hours of clinical interviews. All six defense experts concluded that Chapman was psychotic; five diagnosed paranoid schizophrenia, while the sixth felt that his symptoms were more consistent with manic depression.

Chapman is in the Family Reunion Program and is allowed one conjugal visit a year with his wife, since he accepted solitary confinement. The program allows him to spend up to 48 hours alone with his wife in a specially built prison home. He also gets occasional visits from his sister, clergy, and a few friends.

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Knowledge & Infos

Blepharoplasty (Eyelid Surgery)

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Our human face is composed of various small functional and cosmetic units. One of them is our eyes. Eyes serve both as functional (a sensory organ of sight) and cosmetic (it is used to express emotions and do eye contact), so one can say that eyes play a vital role in both your functionality and beauty.

So, it’s not surprising that people get worried when the areas around their eyes face unwanted changes like drooping eyelids or saggy eye bags, since the area around the eyes play equal role in both aesthetic and functional value. To solve the woes of eyelids, there is a surgical option called Blepharoplasty, which is the surgery around the eyelid area, which might be helpful to those seeking to remedy it.

What is Blepharoplasty?

Blepharoplasty, simply explained, is the plastic surgery operation for correcting defects, deformities, and disfigurations of the eyelids; and for aesthetically modifying the eye region of the face. Medically, according to the Indian Journal of Opthamology, it is a surgical procedure in which the eyelid skin, orbicularis oculi muscle, and orbital fat are excised, redraped, or sculpted to rejuvenate the aesthetic look of the patient along with correction of any functional abnormality.

Why is Blepharoplasty done?

According to WebMD, as skin ages, it gradually loses its elasticity. A lack of elasticity plus the constant pull from gravity causes excess skin to collect on the upper and lower eyelids.
Excess skin on the lower eyelid causes wrinkles and bulges. On the upper eyelids, an extra fold of skin can hang over the eyelashes and get in the way of seeing.

So, Blepharoplasty is done to remove excess skin from the upper eyelids and reduce bagginess from the lower eyelids. It can be done for cosmetic reasons, i.e. to enhance the aesthetic look of an individual or it can to done to improve eyesight of people for whom the hanging eyelid causes partial visual impairment (usually on the elderly population)

Before and After

As you can see in the image below the visible difference from before and after comparison.

Eyelid Surgery (Blepharoplasty) - Health Tourism OnlineHealth Tourism Online

Should I get Blepharoplasty?

If baggy eyelids or droopy eyelids run in your family, or droopy eyelids are giving you trouble in your vision or you simply want to enhance your aesthetic appearance of the eyes, you may consult with a plastic surgeon to discuss your options. Usually, if you are in good health, you can go ahead with the procedure.

What are the risks?

Blepharoplasty, like all other surgeries, carry some risks, but due to the advancement of medical technology, all the risks are either temporary or easily mitigated. However, talk to your doctor to determine if any other factor increases the risk in your case.
Some of the risks include:

  • Infection and bleeding
  • Dry, irritated eyes
  • Difficulty closing your eyes or other eyelid problems
  • Noticeable scarring
  • Injury to eye muscles
  • Skin discoloration
  • The need for a follow-up surgery
  • Temporarily blurred vision or, rarely, loss of eyesight
  • Risks associated with surgery in general, including reaction to anesthesia and blood clots

All these risks can be mitigated and Blepharoplasty is considered safe in general.

If you are thinking of getting Blepharoplasty done, you may book a consult at AAVARAN skin Clinic or use their app to move ahead with the process.

Sponsor of this post is Aavaran Skin and Hair Clinic located at Durbarmarg, Kathmandu, which is known for professional Botox treatment in Nepal through certified doctors. We have collaborated with Aavaran Skin and Hair Clinic in creating informative contents as part of our mission of creating an informed society.

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Knowledge & Infos

What is Botox Treatment

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Perhaps one of the most common non surgical cosmetic treatments in the world is Botulinum toxin therapy, more commonly known as Botox. In this article, we seek to explore what Botox is, the process of this treatment and the pros and cons of this treatment.

What is Botox?

According to the Journal of Drug Sciences, Botulinum toxin (Botox) is a drug made from a toxin produced by the bacterium Clostridium botulinum. In large amounts, this toxin can cause botulism, an illness that affects the nerves.

Botox has been used since the 1970s in the field of ophthalmology, and in the last 20 years, its use has expanded to various health scopes, especially dermatology. In addition to its cosmetic applications, Botox is currently used in the treatment of spasms and dystonias, by weakening involved muscles, for the 60-70 day effective period of the drug. The main conditions treated with botulinum toxin are: Cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck) Blepharospasm (excessive blinking).

How does the process of treatment work?

The Journal of Drug Sciences states that Botulinum toxin exerts its effects by paralyzing skeletal muscle. The pharmacological site of action is at the neuromuscular synapse. In cosmetic applications, a Botox injection, consisting of a small dose of botulinum toxin, can be used to prevent development of wrinkles by paralyzing facial muscles.

The process of administering this treatment is quite short in itself, usually taking less than an hour for the entire session.

When treating fine lines and wrinkles, the dermatologist injects botulinum toxin into targeted muscles on the face or neck. This temporarily relaxes the targeted muscles, causing fine lines and wrinkles to diminish.

According to EmedicineHealth, for the procedure, the patient is placed in a somewhat raised position on the exam table, and the areas to be injected are cleansed with a nonalcohol cleanser, such as Hibiclens or Betadine. Some physicians will apply a topical anesthetic, such as EMLA cream or some alternative, at this time.

The Botox is then injected into the desired areas. Typical injection patterns include about four or five areas on each side of the forehead and two or three areas on either eye area. More areas can be injected by skilled physicians, depending on the type of wrinkles and the desired effect for the patient. It is common for pressure to be applied if an area seems to be bleeding after the injection. While ice is sometimes applied beforehand for comfort reasons, direct pressure is much more effective than ice for control of bleeding and bruising.


Before and after result

As you can see the visible difference. That’s what Botox injection. It smoothens wrinkled skins and thus popular for cosmetic surgery.

Side Effects

According to the American Academy of Dermatology Association, if any patient develops side effects, these tend to be mild and temporary.

The injections, rather than the botulinum toxin itself, cause most mild side effects. For example, a patient may occasionally bruise. If this happens, the bruising lasts about 1 week.

After receiving injections, people have also experienced:

  • Swelling
  • Redness
  • Soreness
  • Bruising
  • Mild headache (uncommon)
  • Weakness in a neighboring muscle, leading to a temporarily droopy brow or eyelid (rare)
  • Signs and symptoms of botulism, including problems breathing, swallowing, or speaking (very rare)

Pros and Cons of the treatment

Pros:

  • – The greatest advantage of this treatment is its ability to take years off of your appearance by eliminating even minor lines and wrinkles.
  • – Another major advantage of this treatment is that it is completely non surgical.
  • – The treatment is also temporary, so if you receive the treatment and are not satisfied with the way it turned out, after 4 to 6 months your face will be back to the previous state.
  • – It also takes a short amount of time for the procedure as compared to other treatments. According to American Association of Dermatology and EMedicine the entire process takes only around an hour, with the actual process of injecting taking less than 10 minutes.
  • – There is no down time, i.e. one can get back to their normal activities (with some precautions) almost immediately after the treatment. Unlike surgeries, this doesn’t take a long rest time.
  • – The results are also visible immediately. It takes between 2 hours to 2 days to visibly observe the results.

Cons:

  • – The advantage of this treatment being temporary also works as the biggest disadvantage, since if one is satisfied with the treatment, they will have to undergo regular treatment every 4 to 6 months.
  • – Botox treatment is slightly expensive. Since this requires regular treatment, the cost can add up.
  • – Since Botox works by temporarily paralyzing some of the facial muscles, it may prevent your face from making certain expressions. Always check how you’ll look after the treatment with your doctor.

In conclusion

Botox is largely considered a safe, non surgical treatment for people seeking to removing the lines and wrinkles from their face. If you seek to get this treatment, you may contact a dermatologist for a consult.

Sponsor of this post is Aavaran Skin and Hair Clinic located at Durbarmarg, Kathmandu, which is known for professional Botox treatment in Nepal through certified doctors. We have collaborated with Aavaran Skin and Hair Clinic in creating informative contents as part of our mission of creating an informed society.

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